Erespal syrup for children: instructions for use, price, reviews, analogues

A syrup in the form of a brownish-yellow liquid, transparent or with slight opalescence, during storage, a precipitate may form which disappears with shaking.

100 ml
fenspiride hydrochloride200 mg

Excipients: flavoring composition with hints of honey smell (flavorings, including natural, sunflower honey, water, ethanol *) - 500 mg, licorice root extract - 200 mg, vanilla tincture (natural vanilla flavor and other components, in t including ethanol *) - 400 mg, glycerol - 22.5 g, methyl parahydroxybenzoate - 90 mg, propyl parahydroxybenzoate - 35 mg, saccharin - 45 mg, sucrose - 60 g, potassium sorbate - 190 mg, purified water - up to 100 ml.

* the total ethanol content in 100 ml of syrup is not more than 0.29 mg.

150 ml - brown plastic bottles (1) - packs of cardboard.
150 ml - brown plastic bottles (1) complete with a measuring cup - packs of cardboard.
250 ml - plastic brown bottles (1) - packs of cardboard.
250 ml - plastic brown bottles (1) complete with a measuring cup - packs of cardboard.

Erespal

Rating 4.0 / 5
Efficiency
Price quality
Side effects

Erespal (Eurespal): 6 reviews of doctors, 44 reviews of patients, instructions for use, analogues, infographics, 2 release forms.


Pharmachologic effect

Anti-inflammatory agent, has an antiexudative effect, prevents the development of bronchospasm. It shows antagonism with mediators of inflammation and allergies: serotonin, histamine (blockade of H 1 histamine receptors), bradykinin. It has a myotropic antispasmodic effect.

When prescribed in large doses, it reduces the production of various inflammation factors (cytokines, arachidonic acid derivatives, free radicals).

Reviews of doctors about Erespal

Rating 5.0 / 5
Efficiency
Price quality
Side effects

I have been working with the drug since 2008. I still prescribe with a usual upper respiratory tract infection and with bronchitis, and with bronchial asthma. Satisfied with the effect. Removed the dye from the syrup. A convenient form of release is both tablets and syrup.

It is rare (met in practice) individual intolerance and, as a result, a side effect: tachycardia. But these are isolated cases.

I recommend the drug both mono and in combination therapy.

Rating 3.8 / 5
Efficiency
Price quality
Side effects

A high-quality drug that dilates the bronchi has an anti-inflammatory effect. If you start treatment for a respiratory viral infection in the earliest period, erespal prevents bacterial complications, reduces the duration of the disease.

Should be prescribed by a doctor, then the expected result will be.

Rating 3.8 / 5
Efficiency
Price quality
Side effects

A good drug for the treatment of acute respiratory viral infections and respiratory tract infections. To prescribe in monotherapy, as colleagues describe below, I do not dare, but in combination it works perfectly. A package of 250 ml syrup has recently gone on sale, which is very convenient when administered to adolescents and children of the younger age category with a long course.

Unfortunately, allergic reactions to the drug are often found.

Rating 5.0 / 5
Efficiency
Price quality
Side effects

A good cough treatment for colds and bronchitis. Possible use in adults and children. Easy dosage of the drug.

The price is high, the quality corresponds to the drug.

Before use, you need to consult a pediatrician. Adverse allergic reactions in the form of urticaria and Quincke's edema are possible.

Rating 3.3 / 5
Efficiency
Price quality
Side effects

2 forms of release.

When this drug first appeared, all the doctors were afraid of it, but I, as a young specialist, was open to a new one. She treated them with bronchitis without antibiotics, even removed bronchial obstruction. But it was while the drug was French. There was also a plus that it was allowed from 0. Then there were changes, the drug became allowed in Russia from 2 years. It began to be produced in Russia. Not only the price, but also the quality has fallen! Syrups children, even non-allergy sufferers! The syrup itself is terribly bitter! As for the pills, I personally can’t take them, the bitterness in my mouth remains so strong that nothing can be removed. About efficiency. This drug is pathogenetic, so the effect occurs on 3-4 days! But again I repeat that the Russian effect is much lower!

Rating 3.3 / 5
Efficiency
Price quality
Side effects

An effective medicine for inflammatory diseases of the bronchial tree. I took it myself, children, wife, patients. Satisfied with the healing effect.

The son with drug allergy and bronchial asthma has an excellent effect and tolerance, and the daughter is intolerant only to Erespal.

Unfortunately, the drug has risen in price as all foreign funds.

Patient reviews about Erespal

Child, 7 years old. Erespal syrup was prescribed for cough. They did not see the result, since a terrible allergy began. The skin looked like after a burn. Six months treated allergies. In March 2019, Erespal was withdrawn from circulation and banned in Russia.

Good remedy "Erespal", son cough quickly cured. The first time a doctor prescribed us, and then we had an allergy to the yellow dye. And now, about 2 years have already passed, the doctor prescribed him to us again, but already this sweetener is not in the composition, and we tried it. True, there was no allergy. So with such a strong cough, I use this Erespal. It helps perfectly.

When I got a job at school, the first time I was very sick. Any virus caused complications and a protracted cough began. Several doctors advised me to “Erespal” in tablets and recommended it as a very effective and modern remedy. Alas, I could not evaluate its effect. As soon as I started taking this medicine, I began to have a terrible arrhythmia, dizziness, a cottony head, consciousness in a fog. After cancellation, side effects have passed. It should be noted that the instruction says about precisely such possible consequences, and I must have just an individual intolerance to me.

Our boy is 10 months old. He got a viral infection with a high fever, a runny nose, then a cough appeared. The pediatrician prescribed Erespal Syrup. We read the instructions, it indicated that you can take it from 2 years old, called the doctor, she said that just last week I was at school, they just discussed this medicine and said that it can be taken from birth. This question quickly became clear and they began to drink syrup; the doctor did not prescribe antibiotics to us. As a result, the cough quickly came to naught, "coughed" quite softly, without a strain. No side effects were manifested in the baby. In our experience, I consider Erespal an effective drug.

Hello. "Erespal" was prescribed to the child several times. A few days later, the cough began to pass. I don’t know if this is due to the use of this particular drug or not, because at the same time they took mucolytics and inhaled. In general, I can’t say that I am for it or against it. But the question of its effectiveness remains open to me. The fewer drugs you can get, the better. Is it worth it to prescribe it with a usual cough of unknown etiology? But for some reason, our doctor does from the clinic, but he, of course, knows better. Think for yourself, decide for yourself, and next time I will try to do without it.

The child got sick. There was a strong wet cough with fever and a runny nose. Turned to the pediatrician. The doctor prescribed Erespal syrup for coughing.They started taking it, literally after the second dose, the child was covered with a rash. Further worse. A terrible allergic reaction to the drug began. The rash turned red, the child was itchy, the throat began to swell, breathing was difficult, digestion was impaired, the child had diarrhea. After taking antihistamines, the child's condition became better. An allergic reaction persisted for about two more days. Then it all went away. After this incident, we do not buy Erespal syrup anymore and do not try to take it. I would not recommend taking this drug for children, especially prone to allergies.

I am ill extremely rarely. But if this happens, it is hard. She got bronchitis, began to suffer a terrible cough, at night it was impossible to sleep, during the day she could not do business. The doctor prescribed Erespal. It is inexpensive, enough for a large number of applications. I had enough for two diseases. After use, it becomes easier, the throat ceases to hurt, calms down, and coughing becomes less painful and rare. For a week, the cough went completely. The medicine now comes first in the treatment of cough.

Very disappointed by the ban on sales of this drug, he was a lifesaver with a complex cough. Always saved from complications of bronchitis. Now my family is busy looking for analogues of a good drug that will not allow it to degenerate from a viral infection into a bacterial disease. I hope that analogues with less side effects will appear.

The child caught a respiratory viral disease. A pediatrician in a city clinic treated, treated, but only everything got worse. There was a dry cough. At night, the child could not sleep because of endless volleys of cough (well, mom and dad respectively also forgot about sleep). We went to a paid clinic and there they explained to us that we had dried our throats with prescriptions of a "free" doctor (we drank Pertussin, after which we appointed Ambroxol). The doctor prescribed Erespal, arguing that he gently dilutes and removes sputum (Ambroxol canceled). And so it happened. Literally in three days we got rid of coughing and silence and a sweet dream reigned in the house.

The drug was prescribed once by my attending physician for bronchitis, and was taken as it was written in the prescription. There were no side effects, after a few days the disease went away. A drug worthy of attention at an affordable price and good quality. And it doesn’t require any complicated reception system, everything is simple, you won’t get lost. This drug really helps. If necessary, I will use it.

"Erespal" in syrup, I began to give the child after a prolonged cough. According to the clinical picture, we were diagnosed with whooping cough. Many doctors agreed that the child has a mutating virus. It was very difficult for us to improve our health, because after this virus we had right-sided pneumonia. And now, for several days now, behind the hospital, procedures, and massage. There was a cough. The doctor prescribed us "Erespal" - this is a syrup, the active substance: fenspride hydrochloride. Pleasant enough composition with vanilla aroma. The child takes it without problems, and the results of treatment are already visible. After the first bottle - 150 ml, coughing attacks began to appear less. The nightly reprise ended. Dry, it seemed as if the smoker's cough also disappeared. Already started to take the second bottle.

We have known Erespal for a long time. First, a pediatrician prescribed a child with a cold, and helped well in the form of syrup. I did not observe allergies in the child. But when I got sick and bought myself pills, then I had side effects. Severe headaches and dizziness began, even I am silent about the therapeutic effect. As soon as I stopped drinking it, all the unpleasant sensations immediately passed.

Erespal suspension for children is our every drug we have been using for seven years now. For the first time I learned about it from our local pediatrician. I like the fact that it is made from natural ingredients, it tastes not very pleasant, but bearable.Moreover, it can be taken with wet and dry cough. Helps on the third, fourth day after administration. We take it three times a day in the dosage that is indicated in the instructions for use. Minus in the configuration of the drug, there is no measuring spoon or cup, which is very inconvenient. I advise and recommend everyone.

I had a commonplace ARVI with a starting dry cough. She took antiviral and Erespal tablets. I don’t know how anyone, but he didn’t help me, but only caused terrible shortness of breath (even from a slow walk) and tachycardia, although there were never and no heart problems. For a long time I could not understand why I felt so bad until I heard the same problem from Erespal from a friend (a few months ago she also took him as prescribed by a doctor). After I stopped taking Erespal, shortness of breath was still about a week. Then it all went away. So with this drug you need to be careful!

From 3 years old, the son has constant laryngitis, Erespal is our salvation. It helps a lot with laryngitis and dry cough, quickly relieves inflammation, literally after 2 days of barking cough and red throat - as always, we drank it for 5-7 days, depending on the severity of the disease, it was also noticed that as soon as we started take it, fever returned to normal, the drug "Erespal" was used in the form of syrup, the only negative is that the child had a slight allergic reaction in the form of urticaria on the 3rd day after administration, so I always give antihistamines with it.

I used Erespal syrup for the first time - I liked it. The child (7 years old) had a wet cough, from the first day she began to give “Erespal” syrup, after a couple of days the cough decreased noticeably, and after another two days it completely disappeared. I did not reveal any side effects in the child. Now I will know about such a good syrup, and the next time I will use only it when coughing.

Erespal syrup is always in my home medicine cabinet. For the first time, daughters at the age of 6 months prescribed the drug with the onset of bronchitis, when severe diarrhea began on antibiotics. "Erespal" helped to cope with a severe cough without consequences and hospitalization. Now "Erespal" helps us with viral rhinopharyngitis, pharyngotracheitis, when it is necessary to quickly and effectively remove inflammation in the upper respiratory tract. Thanks to the anti-inflammatory effect of the drug, antibiotics are often avoided. The children drank the French version of the syrup more readily, the effect was more pronounced.

"Erespal" is a syrup that very well helps with coughing. The syrup does not contain dyes, and also there is no side effect. As I started taking this syrup, the next day the cough eased and gradually disappeared. I advise everyone to take Erespal syrup!

"Erespal" - means number 1 in our first-aid kit for many years. We use it exclusively as a syrup for both adults and children. We use it not only as a cough remedy, but also for any other inflammatory processes - for example, with otitis media. So our doctor advised us, and you can take it for a long time, there is no addiction to the drug. We have never had any side effects! Confidently recommend!

"Erespal" will definitely remain in my medicine cabinet with the note "terrible side effect, do not take." The cough really decreased significantly on the second day. But side effects appeared earlier. After the first reception in the morning I felt a terrible weakness, I could not get out of bed, my head was in a fog, on the second day the weakness was the same, my nose was dry.

For a long time I use this medicine in the treatment of cough in a child. The medicine has a convenient form in the form of syrup, the child takes it with pleasure and does not resist, since Erespal tastes good. The drug has an anti-inflammatory effect, has a quick effect, it can be used in complex therapy in the treatment of cough.

The cough did not go away for several weeks, after taking 6 tablets of this drug, that is, 2 days, the cough went almost completely. BUT! From the very beginning of the reception, such drowsiness and weakness began that literally could not get out of the chair. And the head is in a fog. With this drug you can only get sick in bed, on your feet you can’t recover anymore! And in no case do not drive, the reactions are greatly inhibited!

Erespal appointed us a pediatrician for examination at the hospital. My son often coughs, once again got sick, he treated at home for three days as much as she could. I see that he is worse. We went to the isolation ward, from there they immediately put us in the hospital. At first, the diagnosis was presumably pneumonia, but then it was not confirmed, they made bronchitis. They prescribed Erespal and inhalations, in three days the child stopped coughing badly, and after a week we were discharged. I did not even know this drug before, now I have it in my medicine cabinet.

I took "Erespal" for only 2.5 days, one tablet three times a day, my blood pressure jumped, and my pulse went up to 130 beats. In the morning I took the drug at 7 in the morning, while I was driving to work, I felt squeezed in the throat in the metro area (breathing hard), got out of the car with the feeling that I would faint now. I barely crawled to work, in the office I called an ambulance, since I had never experienced such conditions in my life for 41 years. The ambulance doctor did not specify what I was taking, said to dissolve 5 tablets of glycine (there wasn’t her own in the "suitcase"). I thought I could not survive, weakness, loss of consciousness. I got home by taxi. After that I carefully read the instructions and was horrified, and in the evening, at the appointment with another doctor, my suspicions were confirmed about the side effects from Erespal. She took the pills as prescribed by the doctor. I do not advise anyone to take it.

ARVI. Coughing and chest pain when coughing. The doctor prescribed Erespal tablets. I drank the first pill in the evening, woke up at night from terrible bitterness in my mouth. And in the morning there was a terrible weakness, which was accompanied all day. In general, I do not know if the effect of these pills (which I did not have time to feel) is worth it with such side effects.

Prescribed to a daughter with ARVI and cough. The cough was strong. The child coughed. After the first day of taking this drug, the result became visible. Assigned syrup for 5 days. We drink for three days, but the cough is already moist and almost disappeared.

I met this drug 5 years ago. The child fell ill, and the doctor prescribed Erespal syrup; there was a dry, annoying cough with snot. The action of the drug significantly alleviated the condition of the daughter, it contains substances that relieve swelling, which facilitates breathing and coughing up mucus. In general, the Erespal syrup is our faithful assistant for colds and is a permanent resident of the first-aid kit.

Erespal prescribed a pediatrician to the child. The child had a strong cough, especially the cough intensified during sleep, fever, diagnosis of bronchitis. “Erespal” began to help somewhere on day 3, the cough began to decrease, and after a week there was a residual cough, the child began to cough. After 10 days, the cough stopped altogether. The condition has improved. I really liked the medicine. Before that they drank another medicine, the effect was worse.

"Erespal" can be taken only to those who do not have tachycardia, and everything is in order with the vessels. I had pharyngitis with a dry cough. I took "Erespal" only one day, one tablet three times a day, my blood pressure dropped, and my pulse went up to 130 beats. I thought I won’t survive, weakness, at work I sat on autopilot, I barely reached home. She took the pills as prescribed by the doctor. Only after two days began to recover, the cough decreased, although at what cost. The doctor said that there should not be such an effect. But I experienced on myself, if you suffer from tachycardia, do not accept!

A very effective drug. Thanks to its complex action, it makes a cough productive and relieves bronchospasm.The whole family can sleep peacefully without suffering from a choking cough at night. Also, “Erespal”, the doctor prescribed the daughter with the complex treatment of otitis media (this item is also in the indications for use).

Just a wonderful medicine. I bought in the form of syrup. The composition contains a substance that anesthetizes (this function helped a lot). The cough was lingering, but after applying the weekly course of "Erespal," the cough was completely removed. I advise! It is especially convenient to give to small children (in the form of syrup), it is sweet.

Erespal began to appoint a child from 1 year. There are no less safe analogues, so there wasn’t much choice. They gave, it seemed, helped. But as it was written above - did not save from bronchitis. The medicine is primarily aimed at relieving edema, and has a more anti-allergic effect than fighting a cough. I can’t say that it’s a panacea. But in complex treatment, the drug is good. Of the shortcomings, this is color. Bright orange syrup is difficult to wash. And no matter how carefully you give it, then you need to wash your hands and the bottle itself. Sweet and sticky.

Erespal gave the baby. Outwardly, I did not really like it. Very bright orange color. Judging by the sugars appearing on the neck of the bottle and cap, the syrup is very sweet. Maybe I'm mistaken, because I myself have not tried it. I was afraid of the appearance of a reaction in the child. But nothing happened. Syrup coped with bronchitis quite quickly. In addition, erespal removed the strong nasal congestion with which we had been tormented before this for a couple of weeks. That is, with allergic manifestations from the ENT organs, the medicine also copes well. Therefore, for children I prefer to buy this particular syrup.

I really like the effect of this medicine - the child drinks with pleasure. A good drug, I give my son from 2.5 years old, is always in the home medicine cabinet, for cough of various etiologies.

It was this drug that helped me significantly. Advised friends, acquaintances, it helped not only me. Sputum quickly disappears.

Erespal in a syrup was prescribed by our attending physician a couple of years ago: his son had a fever of 39.5, a red, hoarse throat and nasal congestion. In addition to antibiotics and a list of other drugs, Erespal was prescribed in the prescription. My baby was nervous and refused capsules and aerosols, and he liked this orange syrup. A bit sugary sweet taste, as for me, well, there is an effect. By the way, I give it at the first symptoms of a sore throat. They used to take a small spoon (in the kit), and now the reverse side (those who use this drug understood me). Significantly risen in price this year.

I definitely won’t forget how 4 years ago I managed to catch a cold: either the virus is strong, or it’s just that the treatment by the therapist was incorrectly prescribed, but this cough almost pulled out of me! The cough was so rude that I myself felt terrible from the sounds that I made, not to mention others. ENT prescribed Erespal 1 tablet twice a day: morning and evening. The improvement became noticeably noticeable already after about three days, the cough gradually decreased, until it completely disappeared. I am very glad that I started taking this drug on time and stopped bronchitis, otherwise there would be consequences.

"Erespal" is always in my medicine cabinet. The effectiveness of a strong cough is excellent. I had severe dry bronchitis, which tormented me for two months, pills, syrups did not help. The Erespal doctor prescribed, the next day it was already easier, the cough was not so terrible. As for the children, I’m not sure whether to give them Erispal. Although it is written in the instructions that it is possible to use syrup from the age of 2, I read somewhere that you can take Erispal in tablets from the age of 18, I write it all the time on new packages. Therefore, I am careful not to give my son with bronchitis, but if absolutely necessary, I will take advantage of Erespal.

We got acquainted with this drug at the age of three, when my child had a protracted dry cough.As we just did not treat it, what kind of syrups were not taken, but there was no sense from them. And at the next audition with our attending physician, he advised us to change the syrup to Erespal. I thought that he would not help, and then we will move on to massages and inhalations. But you know, how not surprisingly, the result was not long in coming. Already on the 2nd day of taking the drug, the cough became expectorant, and the next day it completely disappeared. Now we have no problems how and how to treat a cough - Erespal!

Erespal is a good remedy for coughing. My daughter had a cough many times and thanks to this drug he always passes quickly. Not addictive, allergic reactions. Even she herself treated the cough and passed very quickly and without consequences. Quickly relieves symptoms and softens cough.

The child had a protracted dry cough for two weeks and our syrups did not help. Doctors advised inhalation, but I decided to buy something else. Erespal was advised to us in a pharmacy. The baby’s cough was dry, kept him awake at night and tore his throat to the point of hoarseness. We started taking Erespal three times a day in a spoon. On the second day, I noticed improvements - the child began to sleep better. After 3-4 days, it became wet and then came to naught. In addition to coughing, syrup also removes inflammation. I am pleased with the effect, since this syrup was treated without antibiotics.

The doctor prescribed Erespal in syrup to my child with a usual cough, which happens with a severe cold and adenovirus infection. Together with expectorants. And, of course, we coughed as long as we drank these drugs. Later I read in more detail about such drugs and now I know for sure: Erespal is indicated for bronchitis (then it really helped my child quickly soften and increase the effectiveness of cough) and in some cases otitis media (it was prescribed for my child with otitis media as a complication after rhinitis with antibiotics) . When coughing children, most often caused by posterior rhinitis, that is, snot flowing down the back of the throat, it is not needed.

I would like to talk about this wonderful medicine. It really helps with coughing, and quite quickly and effectively, but is also an anti-inflammatory agent. The medicine has no analogues, so you cannot replace it with a cheaper "version". But for children for 3 years, pediatricians prescribe it for free, and it is always available, unlike other drugs from the free list. I give it to my son at the first sign of a cold, as if I were preventing a cough, and it always saves us. It takes 2-3 days, and the cough comes to naught. Wonderful drug.

A very wonderful cough medicine. The grandchildren had a very long cough, they drank a lot of syrups (very different), each for 7 days, while the cough did not stop, but it became wet, expectorant, and dry. And it all started again, the appointment of a new syrup, which once again did not help, tried and alternative methods. As a result: they learned from friends, with the same problem, the doctor prescribed this syrup - Erespal. Consulted with your pediatrician and tried. So on the second day the cough of both grandchildren stopped altogether. And now this is a cough rescue for both me and my grandchildren.

Composition

Composition pills next: each tablet contains the active substance fenspiride hydrochlorideas well as additional substances: hypromellose, calcium hydrogen phosphate, macrogol 6000, silicon dioxide, povidone, titanium dioxide, magnesium stearate, glycerol.

Composition cough syrup next: active substance fenspiride hydrochloride, additional substances: flavoring agent, glycerol, licorice extract, sunset yellow S, propyl parahydroxybenzoate, methyl parahydroxybenzoate, sucrose, saccharin, potassium sorbate, water.

Instructions for use of Erespal syrup

A one-time reception for the baby is from 0.5 to 2 teaspoons. It all depends on weight, age and other features.The duration of admission is determined according to the type of disease.

Detailed instructions for use of Erespal syrup for children:

  • Note: Doctors recommend the use of syrup for children from 2 - 2.5 years. For infants, this treatment option is not suitable.
  • Before giving the child syrup, be sure to shake.
  • The drug is taken before the main meal, that is, on an empty stomach. This will ensure quick and complete absorption of active substances by the body, which guarantees the proper effect of the treatment used.
  • The correct method of admission consider the separation of the medicinal product into two equal parts for use within one day.
  • The maximum number of receptions is up to 3 times a day.
  • Course duration up to 20 days.
  • The exact number of days is indicated by a specialist after examination.

Dosage:

  • babies with a body weight of up to 10 kg should take 2-4 tsp syrup (10 to 20 ml),
  • children from 10 kg and more are given from 2 to 4 tablespoons (30 to 60 ml)
  • teenagers from 14 years old - 3-6 tablespoons (45-90 ml).

Which pharmacies are better to buy + price

Erespal syrup is sold in most online pharmacies, in retail points of sale of the city and is presented in a price range from 226 to 466 rubles.

The most favorable prices for a bottle of 150 ml are offered by pharmacies:

  • City Health - 226 p.
  • Pharmacy.ru - 266 p.
  • Pilli.ru - 224 p.
  • Rigla - 255 p.

Short description

Erespal (INN fenspiride) is an anti-inflammatory and bronchodilator from Les Laboratoires Servier (France), used to treat diseases of the upper and lower respiratory tract. Acute respiratory infections (ARI) affect millions of people of any age and gender each year. The most effective way to treat infectious and inflammatory diseases of the respiratory tract is etiotropic therapy, which assumes an effect not on the symptoms, but directly on the cause of the disease, i.e. on its pathogen. However, in most cases this is not possible due to the lack of objective information about the pathogen, and therefore the principle of influencing the pathogenetic mechanisms of the disease comes to the fore. Whatever the etiology of acute respiratory infections - bacterial, viral, toxic, allergic - the common denominator in all these cases is the inflammatory process. Therefore, anti-inflammatory drugs are chosen as first-line drugs for patients of this profile. Inflammation of the mucous membrane of the upper and lower respiratory tract is accompanied by abundant mucus formation, swelling and proliferation of the mucous membrane, narrowing of the lumen of the bronchi. The use of symptomatic agents in such a situation seems ineffective. Considering that inflammation is in any case at the base of this pathogenetic “pyramid”, the optimal choice is a tool that would not only help to eliminate the damaging agent, but also reduce the severity of the inflammatory reaction by localizing its focus and inhibiting the synthesis of inflammatory mediators acting as catalysts pathological process.

Erespal, which has an affinity for the morphological links of the respiratory system, successfully copes with this task. This drug has a powerful anti-inflammatory effect, comparable to that of glucocorticosteroids, but at the same time, unlike the latter, does not show systemic adverse reactions. Erespal blocks the action of phospholipase A2, acting as an inhibitor of the arachidonic acid cycle, which leads to a decrease in the concentration of inflammatory mediators - prostaglandins, leukotrienes and thromboxanes, and therefore relieves swelling, suppresses excessive secretion of mucus, and eliminates spastic effects. Erespal also acts as an antagonist of histamine and alpha-1-blocker, exerting an antihistamine effect, which consists in thinning sputum and facilitating its evacuation from the respiratory tract. In addition to this, the drug locally reduces the excitability of the nervous system, thereby showing an antispasmodic effect. In other words, Erespal negatively affects all the main parts of the inflammatory process. The drug is available in the form of tablets and syrup. It has a generally favorable safety profile and is well tolerated.It should be taken into account its mild sedative effect (antihistamine component) when performing work requiring increased psychomotor reactivity.

Syrup action reviews

The main active ingredient in syrup is fenspiride. Its mechanism of action is due to the ability to block the production of substances that cause inflammatory processes: swelling of the mucosa and the secretion of increased secretion of the bronchi. Erespal Syrup has bronchodilating propertiessimilar to the antispasmodic effect of papaverine.

  1. With wet cough Fenspiride blocks adrenergic receptors, has an antiexudative effect, normalizes sputum production, and facilitates its evacuation by relieving spasm and expanding bronchi.
  2. Dry cough Erespal syrup containing licorice root extract changes the rheological properties of bronchial secretions, reducing its viscosity and restoring the mobility of cilia, improving coughing. The cough becomes productive, the bronchi are cleared from the accumulation of viscous sputum, and the patient is recovering.

Description of the medication

The main ingredient of the drug is fenspiride hydrochloride. This substance can have a triple effect on the body. Firstly, it reduces inflammation. In addition, it acts on histamine receptors, thereby blocking the production of mucus in the bronchi. Among other things, it has an antispasmodic effect. Therefore, the use of Erespal tablets 80 mg and syrup contribute to the expansion of the bronchi.

The principle of the effect of this drug can fundamentally differ from the work of other antitussive drugs. They fall into two broad categories. Some of them affect dry cough, that is, without the formation of sputum. And others contribute to the process of liquefying this substance, and its removal from the human body. So it is said in the instructions for use with Erespal tablets 80 mg and syrup.

It is worth noting that this tool does not belong to any of these groups. But this does not prevent him from having high efficiency. The reason is that this drug can fight not so much with the consequence of inflammation as it suppresses the mechanism of its occurrence. In addition, the cough reflex is eliminated with fenspiride without acting on the corresponding centers of the brain.

One of the advantages of the drug is that it is useful in the presence of a viral respiratory infection, in which antibiotics do not work. This is achieved due to the fact that the product has strong anti-inflammatory properties. A large proportion of the drug is excreted through the kidneys, and about one tenth through the intestines.

Indications for use of Erespal 80 mg tablets and syrup are discussed below.

Reviews of people

Here's how people respond about Erespal Syrup.

Good cure. When the grandchildren was ill, there was a prolonged severe cough. We drank a bunch of syrups, each for 7 days. The cough did not stop. Changed its shape. It was either wet, then expectorant, or dry. And so in a circle. We were prescribed a new syrup and again to no avail. They tried folk treatment. As a result, friends advised Erespal. They had his doctor prescribed for the same problem. Consulted with a pediatrician and tried. So, on the second day of admission, the cough in the children generally stopped. Now this is our family cough relief.

The child did not pass a dry cough for two weeks. No syrups could help. Doctors advised different, who inhalation, who something else. I decided to try to buy the medicine myself. At the pharmacy, the pharmacist advised Erespal. We took a spoonful of syrup 3 times a day. After the first day of admission, I noticed improvement. The baby began to sleep at night. The cough became wet on 3-4 days, then generally passed. Thank God antibiotics escaped.

I have known Erespal syrup for five years. My daughter had a dry obsessive cough and snot, the doctor prescribed erespal.After taking the drug, the child's condition improved significantly. The substances contained in the preparation, which relieve edema, facilitate breathing and expectoration of sputum. Now Erespal is always in our medicine cabinet. This is a tool that I'm sure.

Erespal is a good cough medicine. My daughter is constantly sick. And we have never done without a cough. And thanks to this syrup everything is instantly treated. Not addictive, allergic reactions. She herself was treated, the cough went very quickly and without consequences. Quickly relieves symptoms and softens cough.

Erespal was prescribed after we had been treating a dry cough and runny nose for a week. No Ambroxols, Lasolvans, etc. just didn’t help! And how surprised I was when Erespal syrup, with a terrible composition, as many say, helped the child on the second day. Therefore, in my review I will not scold Erespal for the synthetic composition, and, moreover, I will not scold for the huge list of side effects, because we simply did not have them during the reception.

In what cases is this drug prescribed?

The main indications for the use of this medication are the following pathologies in a patient: laryngitis along with pharyngitis, bronchitis, bronchial asthma, pneumonia, measles, whooping cough, flu, otitis media and sinusitis.

The natural question arises as to whether Erespal can serve as a replacement for antibiotic therapy in the body. Of course, the answer will be no. The medication acts primarily as an antitussive, and cannot be the only single method in the fight against infectious diseases.

Indications for use of Erespal 80 mg tablets and syrup should be strictly observed.

Indications

Erespal has anti-inflammatory and anti-bronchoconstrictive action. Due to its composition, it is prescribed during complex therapy for children with bronchitis. Additionally, the syrup has an antihistamine effect on the children's body.

He begins to help after a long period of timebut its healing effect is very effective. Many parents who tried this drug, indicated its strong effect and came to the conclusion that it very effectively treats other diseases in children:

  • rhinopharyngitis,
  • laryngitis,
  • otitis,
  • sinusitis,
  • allergic manifestations (allergic rhinitis and others),
  • rhinotracheobronchitis,
  • bronchial asthma,
  • respiratory manifestations (measles, whooping cough, flu).

Most pediatricians concluded that Erespal does not replace antibiotic therapy, but they do not call it an “easy” drug. They called the drug “heavy” for the child’s body due to the fact that it does not have a very beneficial effect on the child’s nervous system.

Pharmacodynamics and pharmacokinetics

Erespal prevents bronchoconstrictionslows down exudation. Anti-inflammatory effect that has fenspiridedue to inhibition of arachidonic acid metabolism. Antibronchoconstrictor effect is produced due to inhibition of the process of allocation of biologically active substances: histamine, serotonin, bradykinin. In addition, the drug blocks α-adrenergic receptors, upon stimulation of which an increase in the production of bronchial secretion is noted.

Prevents bronchospasm. If the drug is prescribed in large doses, it reduces the production of various factors of inflammation.

The medicine is well absorbed from the gastrointestinal tract. The highest concentration of active substance in blood plasma is observed approximately 2.5 hours after oral administration. The half-life is 12 hours.

Approximately 90% of the drug is excreted through the kidneys, the remaining 10% is excreted through the intestines.

Contraindications

The following contraindications to taking the drug are noted:

  • high level of sensitivity to the active substance or other components,
  • children's age up to two years.

Syrup is used with caution to treat people with fructose intolerance, glucose galactose malabsorption, diabetes, deficiency of sucrose or isomaltase, since sucrose is present in the syrup.

Drug effectiveness

Before treatment, it is imperative to familiarize yourself with the instructions for use with which the tool is equipped. The presented medicinal product can be absorbed very well by the body as part of oral administration, it begins to act after a couple of hours. The therapeutic efficacy of the tablets begins to manifest itself after three hours, and the syrup after sixty minutes. This medicine reaches its maximum effect after six hours. In case of an overdose, consult a doctor.

Side effects

If syrup or Еurespal tablets cause any side effects, you should definitely consult a doctor and inform him in detail about what is happening.

When treating with Erespal, the following side effects may occur:

  • In operation of cardio-vascular system: in rare cases, manifested tachycardia, which decreases with a decrease in the dose of the drug.
  • In operation Gastrointestinal tract: gastric and intestinal disorders, pain in the epigastrium, nausea, vomiting and sometimes vomiting are often noted diarrhea.
  • In operation central nervous system: a state of drowsiness is rarely observed, dizziness is sometimes manifested.
  • May be noted astheniavery tired.
  • Reactions skin integument: in rare cases noted hives, erythemarash, sometimes itchy skin may be disturbing.
  • Perhaps the manifestation of sensitivity to the dye, which is part of the product.

Adult Tablet Pill Guide

According to the instructions for use, Erespal 80 mg tablets should be taken in the amount of two pieces per day. With a severe course of the disease, the doctor can increase the frequency of admission up to three times a day. The duration of treatment is also determined by the doctor. In most situations, improvement occurs after two or three days. The drug is usually taken before meals. The instructions for use with Erespal tablets for adults confirm this.

Pills for children under fourteen years of age are prohibited. For the treatment of small patients, it is best to use this medication in syrup format, while observing the rules of the instructions for use.

According to reviews, Erespal for children is a very effective drug.

Action pills reviews

The active ingredient of the drug is fenspiride hydrochloride, which inhibits the metabolism of a special substance - arachidonic acid. It is she who activates inflammation in the lungs. By changing the rheological characteristics of the secretion, the drug eliminates dry cough. With its help, it is possible to reduce sputum synthesis.

Overdose

If an overdose of the drug occurs, you should immediately seek medical help. After an overdose, a condition may be noted drowsinessor excitement, sinus tachycardia, nauseaand vomiting.

In this condition, the patient undergoes gastric lavage, is constantly monitored ECG. If necessary, the vital functions of the body are supported.

Interaction

The abstract indicates that a special study of the interaction of fenspiride with other drugs was not conducted. Due to the likelihood of an increase in sedation when taking histamine H1-receptor blockers, Erespal is not recommended to be taken with sedatives.

What helps

Prevents the direct anti-inflammatory effect of histamine, the effect of histamine on the synthesis of anti-inflammatory metabolites of arachidonic acid. It has a statistically significant antagonistic action on histamine H1 receptors:

  • Prevents bronchoconstriction.
  • It has a pronounced inhibition of secretion of tumor necrosis factor (the effect is dose-dependent).
  • Affects the adrenergic nervous system, being an antagonist of 1-adrenergic receptors.
  • Reduces pathological bronchial hypersecretion, reducing the formation of inflammatory mediators such as histamine, prostaglandins, leukotrienes, cytokines.
  • It leads to a decrease in chemotaxis factors and reduces the migration of inflammatory cells and reduces their total number (the effect depends on the dose).
  • Increases the speed of mucociliary transport in patients with chronic bronchitis by about 30%. (When using 3 tablets per day for one month).

Video

Below is a small video review of Erespal Syrup for children.

In what cases is this drug prescribed?

The main indications for the use of this medication are the following pathologies in a patient: laryngitis along with pharyngitis, bronchitis, bronchial asthma, pneumonia, measles, whooping cough, flu, otitis media and sinusitis.

The natural question arises as to whether Erespal can serve as a replacement for antibiotic therapy in the body. Of course, the answer will be no. The medication acts primarily as an antitussive, and cannot be the only single method in the fight against infectious diseases.

Indications for use of Erespal 80 mg tablets and syrup should be strictly observed.

Indications

Erespal has anti-inflammatory and anti-bronchoconstrictive action. Due to its composition, it is prescribed during complex therapy for children with bronchitis. Additionally, the syrup has an antihistamine effect on the children's body.

He begins to help after a long period of timebut its healing effect is very effective. Many parents who tried this drug, indicated its strong effect and came to the conclusion that it very effectively treats other diseases in children:

  • rhinopharyngitis,
  • laryngitis,
  • otitis,
  • sinusitis,
  • allergic manifestations (allergic rhinitis and others),
  • rhinotracheobronchitis,
  • bronchial asthma,
  • respiratory manifestations (measles, whooping cough, flu).

Most pediatricians concluded that Erespal does not replace antibiotic therapy, but they do not call it an “easy” drug. They called the drug “heavy” for the child’s body due to the fact that it does not have a very beneficial effect on the child’s nervous system.

Composition

The main ingredient, fenspiride hydrochloride, is a rather bitter substance. Therefore, for example, syrup, unlike tablets, contains many different sweeteners with flavorings so that children can take this medicine with pleasure.

According to the instructions for use with Erespal 80 mg, the composition of the tablets is as follows: fenspiride along with disubstituted calcium phosphate, hypromellose, povidone, colloidal anhydrous silicon, magnesium stearate, titanium dioxide, glycerol and macrogol.

What is in the composition of the drug in liquid form? It is sold in bottles with a volume of 150 milliliters, as already noted earlier. In accordance with the instructions for use with Erespal syrup, 1 milliliter of liquid medicine contains 2 milligrams of fenspiride. Other substances that make up the syrup include honey flavoring in combination with licorice root extract, glucose, anise oil, vanilla extract, glycerin, yellow dye, methyl parahydroxybenzoate, propyl parahydroxybenzoate, saccharin, sucrose, potassium sorbate and distilled water.

The Erespal medicine is manufactured by a French pharmaceutical company called Servier Laboratory. This brand is a trusted and reliable supplier. True, as in the case of many other imported medical supplies, the cost of this therapeutic medication may be too high. In this case, it is worth looking for analogues of the described drug containing fenspiride.These include funds “Fenspiride” along with “Erispirus”, “Codestim”, “Fosidal” and some others.

However, as part of the selection of an effective drug, one should focus more than just on the price, since medicines of lower cost may lose in quality. Other antitussive drugs are unlikely to replace Erespal, since they do not have antihistamines and antispasmodic effects. But in more detail we will talk about analogues a bit later. The drug is sold in pharmacies only with a prescription. The product is stored at room temperature, and its shelf life is three years.

Instructions for use with Erespal tablets 80 mg and syrup are very detailed.

Pharmachologic effect

Erespal is an anti-inflammatory drug. Thanks to the constituents, it has an antispasmodic, anti-inflammatory and antihistamine effect.

Pharmacodynamics

Fenspiride prevents the occurrence of bronchoconstriction, reduces the process of exudation. The effect of the drug is based on slowing down the production of biologically active substances. These include histamine, bradykinin, serotonin. Erespal blocks alpha adrenergic receptors.

Pharmacokinetics

The drug is well absorbed from the gastrointestinal tract. The maximum concentration of Erespal in the blood is reached 2.5 hours after its administration. The elimination half-life is 12 hours. Most of the drug is excreted by the kidneys, the remaining - by the intestines.

Drug effectiveness

Before treatment, it is imperative to familiarize yourself with the instructions for use with which the tool is equipped. The presented medicinal product can be absorbed very well by the body as part of oral administration, it begins to act after a couple of hours. The therapeutic efficacy of the tablets begins to manifest itself after three hours, and the syrup after sixty minutes. This medicine reaches its maximum effect after six hours. In case of an overdose, consult a doctor.

What to choose Lazolvan or Erespal?

Earlier, Erespal was more effective in fighting inflammation, and Lazolvan - in sputum discharge. The last drug is prescribed for patients who have a wet cough. Can I take Erespal and Lazolvan at the same time? There are no contraindications, but only a pediatrician can prescribe a joint appointment, since they must be taken according to a certain scheme. In addition, such a need does not arise often. In most cases, you can do with taking one medicine or even without it.

All these drugs are different from Erespal, and after his harm has been proven, the doctor should decide which medicine is best to take, because depending on the type of cough, the treatment should be different and only a specialist can accurately diagnose and select an appropriate dosage regimen.

Adult Tablet Pill Guide

According to the instructions for use, Erespal 80 mg tablets should be taken in the amount of two pieces per day. With a severe course of the disease, the doctor can increase the frequency of admission up to three times a day. The duration of treatment is also determined by the doctor. In most situations, improvement occurs after two or three days. The drug is usually taken before meals. The instructions for use with Erespal tablets for adults confirm this.

Pills for children under fourteen years of age are prohibited. For the treatment of small patients, it is best to use this medication in syrup format, while observing the rules of the instructions for use.

According to reviews, Erespal for children is a very effective drug.

Action pills reviews

The active ingredient of the drug is fenspiride hydrochloride, which inhibits the metabolism of a special substance - arachidonic acid. It is she who activates inflammation in the lungs.By changing the rheological characteristics of the secretion, the drug eliminates dry cough. With its help, it is possible to reduce sputum synthesis.

What helps

Prevents the direct anti-inflammatory effect of histamine, the effect of histamine on the synthesis of anti-inflammatory metabolites of arachidonic acid. It has a statistically significant antagonistic action on histamine H1 receptors:

  • Prevents bronchoconstriction.
  • It has a pronounced inhibition of secretion of tumor necrosis factor (the effect is dose-dependent).
  • Affects the adrenergic nervous system, being an antagonist of 1-adrenergic receptors.
  • Reduces pathological bronchial hypersecretion, reducing the formation of inflammatory mediators such as histamine, prostaglandins, leukotrienes, cytokines.
  • It leads to a decrease in chemotaxis factors and reduces the migration of inflammatory cells and reduces their total number (the effect depends on the dose).
  • Increases the speed of mucociliary transport in patients with chronic bronchitis by about 30%. (When using 3 tablets per day for one month).

Doctors reviews

Erespal is a good medicine for the treatment of cough of any etiology. Allowed for use with wet and dry cough. It is also recommended to use in combination with other antitussive agents. The only thing, it causes drowsiness and therefore it is better not to take it if you are driving a car.

Erespal is a drug of widespread use. It is used for diseases of the upper and lower respiratory tract due to its anti-inflammatory and anti-bronchoconstrictive properties. Erespal, available in tablet form, is used exclusively for adults, children and adolescents are advised to drink Erespal in the form of a syrup. The drug performed well with the complex treatment of Alzheimer's disease. Erespal has proven its effectiveness in the treatment of allergies from the respiratory system, in the treatment of chronic obstructive pulmonary disease.

Erespal tablets help cough for colds and bronchitis. Allowed use in adults. Easy dosage of the drug. The price is high, but the quality is consistent with the drug. Before use, a consultation with a pediatrician is required. There are adverse allergic reactions in the form of urticaria and Quincke's edema.

An effective medicine for inflammatory diseases. I took it myself, children, wife, patients. Satisfied with the healing effect. The son with a drug allergy and asthma has an excellent effect and tolerance, and the daughter is intolerant to Erespal. Unfortunately, the drug has risen in price, like all foreign funds.

Reviews of people

Erespal took only 2.5 days, one tablet three times a day. After that, my blood pressure jumped, and my pulse rose to 130 beats. In the morning I took the drug at 7 in the morning, while I was driving to work, I felt squeezed in the throat in the metro area (breathing hard), got out of the car with the feeling that I would faint now. I barely crawled to work, in the office I called an ambulance, since I had never experienced such conditions in my life for 41 years. The ambulance doctor did not specify what I was taking, said to dissolve 5 tablets of glycine (there wasn’t her own in the “suitcase”). I thought I could not survive, weakness, loss of consciousness. I got home by taxi. After that, I carefully read the instructions and was horrified, and in the evening, at the appointment with another doctor, my suspicions were confirmed about the side effects from Erespal. She took the pills as prescribed by the doctor. I do not advise anyone.

I read online reviews of Erespal. I agree that an effective drug. Thanks to its complex action, it makes a cough productive and relieves bronchospasm. The whole family sleeps calmly, without suffering from a choking cough at night. The doctor prescribed the daughter of Erespal in the complex treatment of otitis media (the current item is in the indications for use).

Prescribed to a daughter with ARVI and cough. The cough was strong. After the first day of taking the drug, the result became visible.Assigned syrup for 5 days. We drink for three days, but already the cough became wet and almost disappeared.

I drank pills strictly according to the instructions when I was on sick leave. After the first pill, I felt an incredible weakness and went to bed. After sleep, I was slightly dizzy. The cough has become much smaller! After the second pill, my head hurt terribly, and after the third pill I had the feeling that I had drunk a lot of alcohol without a snack. “Cotton” head and body. There was a tachycardia, a strange sensation behind the sternum. I decided to drink a pill after dinner, and a pill at night. Side events were easier. I can’t imagine myself at work in a similar condition. Until the end of the week I drank one at night! On the fifth day, the cough went away. For safety, I drank it for the night a couple more days. And, as a bonus, my snot passed. Quickly and without a trace.

She caught a cold and coughed. She did warming, she drank syrup and ambroxol. The doctor prescribed Erespal, the only drug that relieved me of a cough that lasted more than a month.

The whole family drank this terrible drug. Everyone had insomnia and depression. The taste of bitterness in the mouth passed two days after the last dose. I drank four days, did not pass the cough, then quit and everything went away after a couple of days.

Video

Below you will find a small video review of Erespal tablets.

Instructions for use of syrup for the treatment of children

Dosing of syrup for children depends on the weight of the child. It should be selected so that the daily norm does not exceed 4 milligrams per kilogram of mass. Usually for children weighing less than 10 kilograms, two teaspoons of syrup is prescribed per day. For small patients who are heavier than ten kilograms, four tablespoons of the drug are prescribed.

As indicated by the instructions for use, "Erespal" for children in syrup can be used for children from two years of age. Children under two years old should not be given this drug in any case, in any form. For adult patients, this syrup should be taken in three tablespoons (i.e. 45-90 milliliters) per day.

Reviews of doctors and patients

Specialists widely prescribe Erespal, especially for the treatment of adult patients. The advantage of the drug is related to ease of use, as well as the possibility of dose adjustment. Against the background of following the instructions, the development of side effects is rare.

In patients, admired responses are based on the development of a positive effect after a short time from the start of treatment, the possibility of using the drug for a long time, as well as affordable cost.

Known side effects

Like any other drug, Erespal has a number of negative effects that may appear during its use.

Frequency of side effects of Erespal
More often than 1 out of 101 patient out of 10-1001 patient out of 100-10001 patient out of 1000-10.000
No adverse reactions are known.Digestive disorders, nausea, pain in the stomachDrowsiness, allergic reactionsHeart palpitations, which is eliminated by reducing the dose of the drug

When combined with other drugs, the risk of adverse events does not increase, and new and uncharacteristic adverse reactions have not been recorded.

Release form and composition

Erespal is available in the following forms:

  1. Tablets. White color, round shape. They have no specific smell and taste. Available in packaging of 30 pieces. Active ingredient: fenspirida hydrochloride. Excipients: hypromellose, silicon dioxide, povidone, magnesium stearate, titanium dioxide, glycerol, calcium hydrogen phosphate, macrogol 6000.
  2. Syrup. Transparent yellow liquid. Precipitation may occur. Available in bottles of 150 ml. Active ingredient: fenspirida hydrochloride.Excipients: liquorice extract, flavor, sunset yellow, sucrose, glycerol, sphaccharin, water, potassium sorbate, propyl parahydroxybenzoate, methyl parahydroxybenzoate.

Analogs

There are several quite effective analogues of Erespal, matching the active substance and the form of release:

  • Broncho Max. 5 g of the drug contains 10 mg of fenspiride hydrochloride. It effectively fights bronchopulmonary diseases. You can easily cope with the manifestation of allergies from the ENT organs, year-round and seasonal allergic rhinitis, whooping cough symptoms, respiratory manifestations of measles and flu, acute and chronic inflammation of the ENT organs and respiratory tract. BronchoMax, like Erespal, is available in the form of tablets and syrup.
  • Inspiron - Another good analogue of Erespal, which is the same as active ingredients. With its help, various inflammations of the respiratory tract, respiratory symptoms of infectious diseases of measles and flu are treated. Inspiron has a pronounced anti-inflammatory effect, prevents bronchial constriction. Available in the form of syrup and tablets.
  • Fosidal - An effective analogue of Erespal. For the price cheaper. True, it is produced exclusively in the form of syrup, but this does not prevent it from exerting an excellent effect. Due to the same active substance as in Erespal, Fosidal is indicated during laryngitis, sinusitis, rhinopharyngitis, otitis media, chronic bronchitis with respiratory failure, respiratory disorders and bronchial asthma.

The presented analogues of Erespal differ in price and name. They are used during treatment children from 2 years old.

Pharmacology

The anti-inflammatory and anti-bronchoconstrictor activity of fenspiride is due to a decrease in the production of a number of biologically active substances (cytokines (especially TNFα), arachidonic acid derivatives, free radicals), which play an important role in the development of inflammation and bronchospasm.

Fenspiride Inhibition of Arachidonic Acid Metabolism Potentiated by Histamine H Block1receptors, because histamine stimulates the metabolism of arachidonic acid with the formation of prostaglandins and leukotrienes. Fenspiride blocks α-adrenergic receptors, the stimulation of which is accompanied by an increase in the secretion of bronchial glands. Thus, fenspiride reduces the effect of several factors that contribute to the hypersecretion of pro-inflammatory factors, the development of inflammation and obstruction of the bronchi.

Fenspiride also has an antispasmodic effect.

What happened in February 2019

Servier Corporation, being one of the world leaders in the production and sale of original drugs and generics, constantly monitors the effectiveness of its products. At the same time, even after the main clinical studies that are carried out before the appearance of the medicine in pharmacies, the company continues to monitor all unwanted, rare or uncharacteristic reactions to the medicine. For this, of course, the company needs to be given credit.

Among other things, Servier conducts his own research even after the drug is released to the market. Recall that Erespal has been sold in 32 countries for more than 46 years without any complaints from doctors and the public.

In January 2019, Servier received the results of a study that the company's specialists conducted on a group of animals. As a result, it was found that while taking the drug, the risk of arrhythmia in the patient increases. To be more precise, fenspiride can provoke an extension of the QT interval on the cardiogram.

At the same time, such studies in humans were practically not carried out - only a few studies are known that can hardly be called representative.

Since 1973, only five cases of arrhythmia and prolongation of the QT interval on the ECG have been reported in humans. All of them had a favorable outcome and were noted only during the start of production of the drug.Despite this, Servier decided to withdraw Erespal from pharmacies around the world.

In 2019, at least 7,100,000 packages of Erespal (syrup and tablets) worth over 2 billion rubles were sold in Russia alone.

On January 31, a notification letter was sent to the Ministry of Health of the Russian Federation with the results of additional studies of the side effect of the drug. And only 02/14/2019 (In 2 weeks!) Roszdravnadzor announced the withdrawal from circulation of all forms of the drug Erespal.

Dosage

The drug is taken orally, before meals. Shake the syrup before use.

For adults and adolescents, the drug is prescribed for 3-6 tablespoons or 3-6 measuring cups filled up to 15 ml, which corresponds to 45-90 ml / day. The daily dose can be divided into several doses (from 3 to 6).

For children over the age of 2 years, the drug is prescribed at the rate of 4 mg / kg body weight / day. Children weighing up to 10 kg - 2-4 teaspoons or 2-4 measuring cups filled up to 5 ml, which corresponds to 10-20 ml / day, can be added to a bottle with food. Children weighing more than 10 kg - 2-4 tablespoons or 2-4 measuring cups filled up to 15 ml, which corresponds to 30-60 ml / day. The daily dose can be divided into several doses (from 2 to 4).

1 tablespoon or 1 measuring cup, filled up to 15 ml (15 ml syrup), contains 30 mg of fenspiride hydrochloride and 9 g of sucrose.

1 teaspoon or 1 measuring cup filled up to 5 ml (5 ml of syrup) contains 10 mg of fenspiride hydrochloride and 3 g of sucrose.

The duration of treatment is determined by the doctor.

Drug interaction

Special studies on the interaction of fenspiride with other drugs have not been conducted.

Due to the possible increase in the sedative effect when taking histamine H 1 receptor blockers, it is not recommended to use the drug Erespal syrup in combination with drugs that have a sedative effect, or together with alcohol.

Special instructions

The composition of the drug includes parabens (parahydroxybenzoates), as a result of which the administration of this drug can provoke the development of allergic reactions, including deferred.

When prescribing the drug to patients with diabetes, it is necessary to take into account that Erespal syrup contains sucrose (1 teaspoon or 1 measuring cup filled with up to 5 ml of syrup - 3 g of sucrose = 0.3 XE, 1 tablespoon or 1 measuring cup filled with up to 15 ml of syrup - 9 g of sucrose = 0.9 XE).

Influence on the ability to drive vehicles and control mechanisms

Studies on the effect of the drug Erespal on the ability to drive vehicles and work with mechanisms have not been conducted. Patients should be aware of the possible development of drowsiness when taking Erespal, especially at the beginning of therapy or when combined with alcohol, and should be careful when driving vehicles and when performing work requiring a high speed of psychomotor reactions.

Pregnancy and lactation

Data on the use of the drug Erespal in pregnant women are absent or limited. Taking the drug during pregnancy is not recommended.

Therapy with fenspiride is not a reason for terminating the onset of pregnancy.

Do not use Erespal during breastfeeding due to lack of data on the penetration of fenspiride into breast milk.

Side effects

The use of erespal can lead to the appearance of adverse reactions. It is recommended to consult a doctor with these types of ailments:

  • the occurrence of moderate tachycardia (lowering the dosage of the drug most often solves the problem),
  • nausea, epigastric pain, gastrointestinal upsets, vomiting and diarrhea,
  • drowsiness, dizziness,
  • increased fatigue and asthenia,
  • allergies in the form of erythema, rash, urticaria, skin itching and angioedema.

FAQ: Frequently Asked Questions

What is the price of erespal?

The average price in pharmacies is 200-300 rubles per bottle of 150 ml.

Can I take Erespal for very young children?

The instructions for use say that the drug is prescribed for children from 2 years. But still, with respiratory diseases, ENT pathologies, erespal is also prescribed for newborns. It is allowed to take Erespal syrup from the age of 2 years, having studied in detail its composition and effects on the body and consulted with a doctor.

How many days are allowed to drink Erespal syrup?

The dosage and duration of erespal therapy are prescribed by the local pediatrician. The instructions for the drug indicate that the course of therapy is from 20 to 30 days.

Pregnancy and lactation

Data on the use of Erespal ® in pregnant women are absent or limited. The use of the drug during pregnancy is not recommended.

Therapy with fenspiride is not a reason for terminating the onset of pregnancy.

Erespal ® should not be used during breastfeeding due to the lack of data on the penetration of fenspiride into breast milk.

Antibiotic or expectorant

Many patients during the treatment of colds and respiratory diseases, try to choose drugs so that they have the maximum result. That is why you need to know whether Erespal is an antibiotic or not, and how it affects the body. This tool does not apply to antibacterial.

The drug "Erespal" can eliminate the inflammatory process, but can not replace antibiotic therapy. Therefore, if necessary, it is taken along with antibiotics. And since this drug is also able to have a sedative effect, it is not recommended to prescribe it simultaneously with sedatives and tranquilizers.

During pregnancy and lactation

There is no data on the use of fenspiride hydrochloride during pregnancy or they are limited. But if pregnancy was detected during the treatment with Erespal, there is no need to interrupt it.

There is no data on whether fenspiride passes into breast milk. Therefore, when feeding, it is recommended not to take this tool. Infectious diseases of the respiratory tract should be treated with other means, for which a woman needs to see a doctor.

Why syrups should not be given to children under two years of age

Such medicines are prohibited and are not prescribed by doctors to very small patients. And there are reasons for this.

  1. Children at the age of one year do not know how to expectorate sputum, and syrups are aimed specifically at expectoration, as they dilute sputum. As a result, children may have difficulty breathing. In some cases, it can go to hospitalization.
  2. Coughing occurs when mucus accumulates in the airways. Small children can be given more fluids, preferably warm water. Doctors also recommend that you often ventilate the bedroom where the sick child is (not only sleeping, but also playing).
  3. The best prevention and treatment is flushing the nose with saline. The doctor may prescribe other means that are specially adapted for very young children. Some apply even from birth.
  4. Basically, in Russia there are drugs that include acetylcysteine ​​and carbocysteine: Dr. Mom, Mukomist, Bronkhobos, Fluditek. Mucolytic agents are not contraindicated in children under two years of age, but they are taken under the constant supervision of treating doctors.
  5. Acetylcysteine ​​can seriously harm the health of a small patient: for example, cause a number of negative manifestations, among which there are bronchospasm.In large quantities, this substance is capable of causing bleeding in the lungs, leading to hypersecretion of accumulating mucus, impaired liver function, and renal failure.
  6. Carbocysteine ​​is similar in its effect to acetylcysteine, but in Russia it is among those allowed for children. Although in some countries, for example, in France, the United States, cough syrups are strictly prohibited and even seized from those who previously purchased them. At many consultations, scientists and leading experts in the field of medicine and pharmacology came to the conclusion that cough syrups, especially those containing the above substances, as well as preservatives, flavorings and colorants do more harm to children than good.

Erespal syrup for children may well be used as a remedy, but only at the age of two years, unless, of course, the attending physician himself prescribes this remedy in crumbs. Although many pediatricians, despite contraindications, prescribe this drug, parents need to be more vigilant and learn the rules of use and contraindications, from what age you can use this or that medicine.

For children over 2 years old, this syrup will help to cure cough and bronchospasm. According to some reviews, it is better to use it at the last stage of the disease or when the cough is dry. It is important to know which drug and cough can help. Esperal is believed to be an antispasmodic and antihistamine. It is used both as the main and as additional. Often he is discharged paired with Lazolvan.

How does it work

Erespal is a unique medication that prevents the spread of the inflammatory process in a short time and has bronchodilating properties.

The drug blocks the mediators of the inflammatory process, removing not only the symptoms of the disease, but also its root cause, acting directly in the focus of inflammation.


The medicine affects the activation of the ciliary epithelium, normalizes gas exchange in the lung tissue, stimulating the liquefaction of mucus.
Fenspiride blocks histamine receptors, inhibits the production of arachidonic acid, which plays an important role in the appearance of edema, bronchospasm and hyperproduction of sputum.

Thus, the tool acts in several directions:

  • helps to reduce the clinical manifestations of infectious diseases - relieves swelling of the mucous membranes, relieves pain symptoms in the throat, cough and runny nose,
  • affects the focus of the inflammatory process,
  • restores nasal breathing,
  • does not require intensive concomitant treatment,
  • practically does not provoke allergic reactions,
  • can be combined with other agents without reducing their therapeutic effectiveness,
  • shortens the period of the disease, accelerating the cure,
  • can be prescribed to young children from 2 years.

When taken orally, the drug in tablets reaches its highest concentration after 6 hours, in syrup after 3 hours. 12 hours after use, the substance is removed by the kidneys.

Special recommendations

Quite often, patients are interested in the question of whether Erespal is an antibiotic. Doctors say that this tool is not such. Moreover, it cannot replace antibiotic therapy.

For patients with diabetes, the medication in question is prescribed only in tablets. This is due to the fact that the syrup contains sucrose.

It should also be noted that due to the presence of sunset yellow in a suspension in patients with intolerance to acetylsalicylic acid and NSAIDs, bronchospasm may occur.

Studies to draw conclusions about the effect of this drug on a person’s ability to drive vehicles and work with complex mechanisms have not been conducted. However, it should be said that with its use, the patient may experience drowsiness, especially if the medication was combined with alcohol or sedatives.

Features of the drug

The need to take the described drug annually occurs in many people. The reason for this may be a combination of many different factors, in particular such:

  • infection with viruses or bacteria,
  • toxin poisoning,
  • allergy.

For the high-quality treatment of colds, it is necessary to carry out complex therapy and apply drugs that help eliminate viruses and bacteria. They help to suppress the processes of reproduction and activity of microorganisms that provoke the disease.

For colds and flu, inflammation of the airways is considered the main symptom. And the Erespal drug has a complex effect, namely:

  • anti-inflammatory
  • antihistamine
  • normalizes mucus separation.

The medicine prevents the occurrence of swelling of the mucosa, prevents the occurrence of spasms in the bronchi. That is why, answering the question: “Erespal” is an antibiotic or expectorant, it can be said for sure that this is a very good drug, but it does not apply to these groups of drugs. At the same time, it helps to eliminate the inflammatory process, reduces the viscosity of sputum and promotes its rapid elimination. Although it is recommended to use antibacterial and expectorant drugs, for example, such as Prospan and Lazolvan, in addition to the mentioned agent.

What cough to take

Before using the drug, you need to understand what cough it helps. Cough is dry, or unproductive, and wet (productive). Their differences are simple. A productive cough is characterized by expectoration of sputum and mucus. Thus, the airway is cleansed, which contributes to the rapid recovery of the patient.

Erespal works well with wet cough, as it stimulates the rapid elimination of sputum from the body. Dry cough is considered unproductive due to the lack of bronchial secretion, which prevents the purification of the lungs. For its treatment, various drugs are used - antitussive, bronchodilators. The tool should facilitate the transition of unproductive cough to wet. Erespal helps in this - it expands the bronchi and reduces inflammation.

Know! Thanks to its mode of action, the anti-inflammatory syrup Erespal is effective for any type of cough.

Use during pregnancy and lactation

Experts do not recommend the use of Erespal syrup, because there are no clinical data and studies.

It is also unknown whether the main element of fenspiride is excreted in breast milk. Therefore, when breastfeeding, you also do not need to use this medicine. In case of illness, it is recommended to purchase medications prescribed by the attending physician, and only under his supervision.

Treatment with Erespal syrup is not a reason for abortion.

Always helps: a range of indications for prescribing the drug

Possessing a unique mechanism of action, Erespal syrup, in fact, is a universal cough medicine for children. He equally successfully copes with both unproductive and “wet” coughs and manages to help even with viral infections, when antibiotics are useless. That is, you can prescribe it without thinking about the type and origin of cough.

For small patients, it is prescribed for:

  • rhinopharyngitis (inflammation of the nasopharynx),
  • laryngitis (an inflammatory process localized in the vocal cords),
  • tracheobronchitis
  • bronchitis
  • infectious diseases accompanied by cough (SARS, whooping cough, measles, flu, pleurisy, pneumonia),
  • bronchial asthma, COPD,
  • sinus, frontal,
  • otitis media.

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How does he act

Erespal and syrup taken internally begin to act within half an hour, and blood plasma accumulates the maximum useful dose after 2, 5 hours from the moment of ingestion in the case of syrup and 6 hours after taking the pill.Excretion of the drug is carried out through the kidneys and partially through the intestines.

In the respiratory tract with inflammation on the surface of the mucous membrane, a large number of biological catalysts of inflammation processes accumulate, which only strengthen them. Among them are cytokines, free radicals, tumor necrosis factors alpha and arachidonic acid derivatives. These substances stimulate the mucous receptors to produce more viscous secretions and contribute to the tension of smooth muscle fibers in the walls of the bronchi, causing bronchospasm.

The main active substance of Erespal is fenspiride hydrochloride, which blocks histamine H1 receptors and alpha-adrenergic receptors, as a result of which the spasm of the smooth muscles of the bronchi is removed, the secretion of fluid secretion and the degree of edema of the mucous membranes are reduced.

In what form is produced and how is the drug dosed

Erespal tablets
There are syrup and tablets of Erespal of French and Russian origin.

The syrup contains 2 mg of fenspiride hydrochloride per 1 ml, the volume of the bottle is 150 ml.

The tablets in the shell contain 80 mg fenspiride hydrochloride, 30 tablets are in a cardboard box.

Adults and children after 14 years of age are usually prescribed one tablet of 80 mg in the morning and one more in the evening (possibly three times) and Erespal syrup one (or two) tablespoons before breakfast, lunch and dinner.

In the form of syrup can be given even to infants. The dose is calculated based on body weight. A child weighing up to ten kilograms per day is prescribed no more than four teaspoons, and older children under the age of sixteen are recommended up to four tablespoons of syrup per day.

The medicine is taken regularly before meals (Erespal for young children is mixed in a bottle), the treatment lasts about a month. Shake the syrup before use.

In case of overdose, emergency medical attention is required. There is severe drowsiness or severe agitation, accompanied by a heartbeat, nausea and vomiting. It is necessary to rinse the stomach and monitor vital functions. contact-form-7>

Limitations and contraindications for use

The instructions for use attached to the Erespal preparation warns that during treatment, side effects may occur:

  • abdominal pain, nausea, sometimes vomiting and diarrhea,
  • allergic manifestations of a rash, redness, urticaria, in rare cases, Quincke's edema, skin itching,
  • palpitations are rare
  • drowsiness, rarely fatigue and dizziness.

You can not use the drug for people with special sensitivity to the active and excipients present in the composition of the drug (especially to methyl paraben and propyl paraben from syrup). Tablets are forbidden to give to children under the age of fourteen.

The drug is not recommended for pregnant and lactating women, due to the lack of confirmed data on the possible effect on the fetus and the ability of the drug to pass into breast milk.

Used with caution

Use Erespal carefully
Violation of the metabolism of sugars in the body, and diabetes mellitus in particular, is a reason for careful use, given that Erespal syrup contains sucrose in the following dosage: 3 g (0.3 XE) contains 1 teaspoon of the drug, and 9 g (0 9 XE) sucrose - canteen. Therefore, such patients should control blood sugar during treatment with syrup.

Special studies studying the effect of Erespal on the speed of reaction and attention when driving a car have not been carried out, however, in cases where a quick reaction is required, it should be borne in mind that the development of drowsiness during treatment can interfere with it.

Also, the question of the mutual influence of Erespal and other drugs has not been investigated. They suggest a likely increase in drowsiness if you drink this drug and a remedy with sedative properties. Alcohol for a similar reason is not worth taking with tablets or syrup.

Aspirin and drugs from the NSAID group can contribute to the manifestations of allergies, therefore, their combination with Erespal should be used with all possible caution.

DOCTOR consultations online

Patient: it is necessary to be vaccinated, and the child has urticaria. Doctor: before vaccination, it is advisable to donate blood for antibodies to cytomegalovirus and Epstein-bar virus. It cannot be excluded that the baby suffered a mild form of mononucleosis. Then you will have a 3-minute medication flow from vaccination. of the month

Patient: Can the presence of these viruses cause hives? or as a consequence? appeared on the day of the analysis ...

Doctor: The virus itself does not cause hives, but can provoke a change in immunity, which is manifested by urticaria. Most likely, it is not directly related to the delivery of the analysis. Do you have urticaria now?

Doctor: How long does it last? How common? What are you treating?

Patient: 2 days .... At first it was on the neck, now on the stomach and back ... ... It is not red. The child is slightly worried. While I’m not treating anything - but, it seems, it's time ... ..tk. has become more. I did not introduce new products! And what do you advise? They made an appointment with the infectious disease specialist only after 2 weeks ...

Doctor: Be sure to drink sorbents and antihistamines Enterosgel, for example, and Zirtek 5 cap 2 r / day Lactofiltrum is possible if Enterosgel does not work

Patient: How many days to give Zyrtec? and lactofiltrum?

Doctor: Think about whether the appearance of urticaria, for example, is associated with a walk in any particular place? At this age, urticaria may occur as a reaction to flowering. Lactofiltrum 5 days, sirtek 10-14. New products, of course, do not give. Try to drink more with plain water.

Patient: In this sense, we are not allergic. We only have colic for milk. We have already talked with a gastroenterologist. What other surprises can be expected if it is a virus? We’ll go to take tests tomorrow ...

Doctor: Frequent ARVI, liver enlargement Allergy, as a rule, does not happen at an early age, forms over time. So watch.

Application features

For some diseases involving antibiotics and other drugs, Erespal is part of a comprehensive therapy. It is allowed to take it at the same time as antibacterial drugs, but in no case can it be their replacement.

It is not recommended to use alcohol in the treatment and use sedatives: this can enhance the sedative effect of the drug. It is also worth considering when driving a car or working with mechanisms.

Erespal syrup reviews for children are positive, but some parents may be confused by its price, and they are interested in cheaper analogues of this medication. The difference in price can be small, but significant for someone, especially if you have to buy a lot of medicines. There are many other drugs that have the same active substance. These include:

  • Syrups: Bronchomax, Sinuspal, Inspiron, Fosidal, Erispirus, Siresp.
  • Tablets: Amispiron IC, Bronchomax, Inspiron, Epistat, Eladon.

When deciding to replace with an analogue, consult a doctor and take into account the concentration of the active substance, as well as other components.

For children how to take?

Given the high biological activity of the drug, for children it should be used only according to the instructions for use). According to some doctors, ergoferon (as an etiotropic drug) should be used along with erespal, but this has no scientific justification (in view of the unproven effectiveness of the latter).

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